The total distance from Ohio to South Carolina is 464 miles or 746 kilometers. This distance is equal to 403 nautical miles and an average flight takes 56 minutes to cover this distance with an average speed of 500 mph, which is equivalent to 805 km/hr or 434 knots. On the other hand, if you travel by road with an average driving speed of 55 mph or 88.5 km/hr you can cover this distance in 8 hours and 26 minutes.
